Development of Next Generation Dynamic Cell Culture Model:
3D Microfluidic Magnetic Cell Culture
Wellcome!
MNP Research Group
The MNP research group is currently working on fluorescent micro/nanoparticle synthesis, drug discovery-toxicity testing kits for point-of-care and target delivery, antimicrobial materials, and microfluidic water treatments with two ongoing projects. The research interests focused on green synthesis techniques, hybrid particles, and 3D cell culture models. Our contributions appeared in peer-reviewed journal articles, patents, and projects. We collaborate with several universities and industrial partners around the world.
Thanks for your interest!
citation
article
Project done
Research Applications
Separation Systems
Bioprocessing and Chromatography:
• Bioseparation techniques for the purification of proteins, antibodies, and other biopharmaceuticals.
• Continuous bioprocessing methods for increased efficiency and productivity.
• Liquid Chromatography (HPLC): High-performance liquid chromatography is widely employed to separate biomolecules based on various properties.
Nanotechnology in Separation:
• Application of nanomaterials in separation processes for enhanced selectivity and efficiency.
• Nanofluidic devices for precise control in separation at the nanoscale
Cell Culture
Cell Culture Techniques:
• Monolayer Culture: Cells adhere to the substrate and form a single layer.
• 3D Culture: Mimics the in vivo environment, promoting more natural cell behavior.
• Dynamic Culture: Cells are exposed to controlled mechanical forces and shear stress.
Drug Discovery:
• Screening and testing potential drugs before moving to in vivo studies,
• Evaluate the toxicity of chemicals and drugs, reducing the need for animal testing.
Catalyst
Heterogeneous Catalysts:
• Supported Noble Metal Catalysts: Palladium (Pd), platinum (Pt), and other noble metals are supported on various materials like activated carbon for catalytic reduction of contaminants.
Biosensors
Surface-enhanced Raman scattering (SERS)
• the enhanced signals provided by nanostructured metallic surfaces
• Offers high sensitivity and specificity for detecting and identifying biological molecules
Research Interest
MNP research group
Polymer Particles
Monodisperse polymeric particles
• Microparticles from 1µm to 10µm in size with different functional groups (carboxyl, amin, hydroxyl, zwitterionic …)
Hybrid Particles
• Polymer-Metal Hybrids
• Polymer-Inorganic Nanoparticle Hybrids
• Lipid-Polymer Hybrids
Lipid Particles
• Solid lipid nanoparticles (SLNs)
• Nanostructured lipid carriers (NLCs)
• Lipid nanoparticles (LNPs)
Magnetic Particles
• Superpara magnetic iron nano oxides (SPION) particles
• Magnetic nanoparticle decorations
Metal Particles
• Gold nanoparticles
• Silver nanoparticles
Janus Particles
• Magnetic and fluorescent janus particles
Our Latest News
MNP Research Group
Microfluidic vs. batch synthesis of fluorescent micro/nanoparticles
Fluorescent particles play a crucial role in nanomedicine and biological applications such as imaging, diagnostic tools, drug delivery, biosensing, multimodal imaging, and theranostics. This report presents a novel synthesis method and comparative study for synthesizing fluorescent particles in microfluidic continuous and batch-type reactors. Glycidyl methacrylate (GMA) and ethylene glycol dimethyl…
Polymer2024-METU
We are grateful for the opportunity to participate in Polymer2024 at METU in Ankara, where our MNP research group had the privilege of presenting our latest studies. This event provided a wonderful platform to connect with talented young scientists and explore potential collaborations. We extend our heartfelt thanks to the…
ECIS2024 Copenhagen
We are happy to participate in ECIS2024 in Copenhagen, where we presented our latest research on hybrid particles. This event also provides a valuable opportunity to engage with bright young scientists and explore potential collaborations. ECIS 2024 Conference – European Colloid and Interface Society