TUBITAK 1001- 55k USD
15 Dec 2023- 15 Jun 2026
Summary
Preclinical medicine, vaccine trials, and personalized medicine are gaining importance for scientific communities. Cell culture is an indispensable tool for preclinical data analysis in cell biology, cell division mechanisms, material testing, and drug development. The most popular cell culture models are two-dimensional (2D) as a monolayer. However, this model fails to mimic the natural cell environment because most matrices lack cell-cell and cell-extracellular circuits. In recent years, in-vitro three-dimensional (3D) cell culture models have been eliminating the inadequacy of 2D models by better imitating the in-body natural environment. Our project, proposing a new generation dynamic magnetic 3D (m3D) microfluidic cell culture model, aims to solve the problems experienced in 3D cell culture models and magnetic 3D cell culture models in microfluidic systems.